| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK10 | SFN | Ser186 | FHYEIANsPEEAISL | phosphorylation down-regulates | 15071501 | SIGNOR-124005 |
| MAPK9 | SFN | Ser186 | FHYEIANsPEEAISL | phosphorylation down-regulates | 15071501 | SIGNOR-124027 |
| MAPK8 | SFN | Ser186 | FHYEIANsPEEAISL | phosphorylation down-regulates | 15071501 | SIGNOR-124016 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK10 | phosphorylation up-regulates → | SFN PSer186 | phosphorylation down-regulates ⊣ | SFN | 15071501 | SIGNOR-124005 |
| MAPK9 | phosphorylation up-regulates → | SFN PSer186 | phosphorylation down-regulates ⊣ | SFN | 15071501 | SIGNOR-124027 |
| MAPK8 | phosphorylation up-regulates → | SFN PSer186 | phosphorylation down-regulates ⊣ | SFN | 15071501 | SIGNOR-124016 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK10 | phosphorylation down-regulates | SFN | SIGNOR-124005 |
| MAPK9 | phosphorylation down-regulates | SFN | SIGNOR-124027 |
| MAPK8 | phosphorylation down-regulates | SFN | SIGNOR-124016 |
