Entity Details

Name PRKACA_Thr312
ID P32245
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKACAMC4RThr312RSQELRKtFKEIICCphosphorylation
down-regulates activity		12639913SIGNOR-250017
GRK2MC4RThr312RSQELRKtFKEIICCphosphorylation
down-regulates activity		12639913SIGNOR-247770
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKACAphosphorylation
up-regulates
→
MC4R
PThr312		phosphorylation
down-regulates
⊣		MC4R12639913SIGNOR-250017
GRK2phosphorylation
up-regulates
→
MC4R
PThr312		phosphorylation
down-regulates
⊣		MC4R12639913SIGNOR-247770
Regulator Mechanism/Effect Target SIGNOR-ID
PRKACAphosphorylation
→
down-regulates activity 		MC4RSIGNOR-250017
GRK2phosphorylation
→
down-regulates activity 		MC4RSIGNOR-247770