Entity Details

Name GTF2H1
ID P32780
Role kinase
Enzymatic Domains
BSD 1 99-154
PROSITE-ProRule
BSD 2 180-232
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
GTF2H1E2F1Ser403PEEFISLsPPHEALDphosphorylation
down-regulates quantity by destabilization		10428966SIGNOR-251259
GTF2H1E2F1Thr433DCDFGDLtPLDFphosphorylation
down-regulates quantity by destabilization		10428966SIGNOR-251260
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
GTF2H1phosphorylation
up-regulates
→
E2F1
PSer403		phosphorylation
down-regulates
⊣		E2F110428966SIGNOR-251259
GTF2H1phosphorylation
up-regulates
→
E2F1
PThr433		phosphorylation
down-regulates
⊣		E2F110428966SIGNOR-251260
Regulator Mechanism/Effect Target SIGNOR-ID
GTF2H1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		E2F1SIGNOR-251259
GTF2H1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		E2F1SIGNOR-251260