| Name | CSF2RB |
| ID | P32927 |
| Role | substrate |
| Enzymatic Domains |
Fibronectin type-III 1 133-240 PROSITE-ProRule
Fibronectin type-III 2 339-436 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN11 | CSF2RB | – | dephosphorylation up-regulates | 9162089 | SIGNOR-48557 | |
| BCR-ABL | CSF2RB | – | phosphorylation up-regulates activity | 8758906 | SIGNOR-255814 | |
| PTPN6 | CSF2RB | Tyr628 | PPPGSLEyLCLPAGG | dephosphorylation down-regulates | 11812650 | SIGNOR-114597 |
| PTPN6 | CSF2RB | Tyr628 | PPPGSLEyLCLPAGG | dephosphorylation down-regulates | 9162089 | SIGNOR-48561 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN6 | dephosphorylation down-regulates ⊣ | CSF2RB PTyr628 | dephosphorylation up-regulates → | CSF2RB | 11812650 | SIGNOR-114597 |
| PTPN6 | dephosphorylation down-regulates ⊣ | CSF2RB PTyr628 | dephosphorylation up-regulates → | CSF2RB | 9162089 | SIGNOR-48561 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN11 | dephosphorylation → up-regulates | CSF2RB | SIGNOR-48557 |
| BCR-ABL | phosphorylation → up-regulates activity | CSF2RB | SIGNOR-255814 |
| PTPN6 | dephosphorylation down-regulates | CSF2RB | SIGNOR-114597 |
| PTPN6 | dephosphorylation down-regulates | CSF2RB | SIGNOR-48561 |