| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN6 | CSF2RB | Tyr628 | PPPGSLEyLCLPAGG | dephosphorylation down-regulates | 11812650 | SIGNOR-114597 |
| PTPN6 | CSF2RB | Tyr628 | PPPGSLEyLCLPAGG | dephosphorylation down-regulates | 9162089 | SIGNOR-48561 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN6 | dephosphorylation down-regulates ⊣ | CSF2RB PTyr628 | dephosphorylation up-regulates → | CSF2RB | 11812650 | SIGNOR-114597 |
| PTPN6 | dephosphorylation down-regulates ⊣ | CSF2RB PTyr628 | dephosphorylation up-regulates → | CSF2RB | 9162089 | SIGNOR-48561 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN6 | dephosphorylation![]() down-regulates | CSF2RB | SIGNOR-114597 |
| PTPN6 | dephosphorylation![]() down-regulates | CSF2RB | SIGNOR-48561 |