Entity Details

Name CDK2_Thr110
ID P33991
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CyclinA2/CDK2MCM4Thr110PRSGVRGtPVRQRPDphosphorylation
down-regulates		12714602SIGNOR-217352
CDK2MCM4Thr110PRSGVRGtPVRQRPDphosphorylation
down-regulates activity		12714602SIGNOR-100889
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CyclinA2/CDK2phosphorylation
up-regulates
→
MCM4
PThr110		phosphorylation
down-regulates
⊣		MCM412714602SIGNOR-217352
CDK2phosphorylation
up-regulates
→
MCM4
PThr110		phosphorylation
down-regulates
⊣		MCM412714602SIGNOR-100889
Regulator Mechanism/Effect Target SIGNOR-ID
CyclinA2/CDK2phosphorylation
img/direct_inhibition.png
down-regulates 		MCM4SIGNOR-217352
CDK2phosphorylation
→
down-regulates activity 		MCM4SIGNOR-100889