| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN11 | CTNNA1 | Tyr148 | LADMADVyKLLVQLK | dephosphorylation down-regulates | 16767162 | SIGNOR-147075 |
| CSNK2A1 | CTNNA1 | Ser641 | TPEELDDsDFETEDF | phosphorylation down-regulates | 19941816 | SIGNOR-161847 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN11 | dephosphorylation down-regulates ⊣ | CTNNA1 PTyr148 | dephosphorylation up-regulates → | CTNNA1 | 16767162 | SIGNOR-147075 |
| CSNK2A1 | phosphorylation up-regulates → | CTNNA1 PSer641 | phosphorylation down-regulates ⊣ | CTNNA1 | 19941816 | SIGNOR-161847 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN11 | dephosphorylation down-regulates | CTNNA1 | SIGNOR-147075 |
| CSNK2A1 | phosphorylation down-regulates | CTNNA1 | SIGNOR-161847 |
