| Name | NOS2 |
| ID | P35228 |
| Role | substrate |
| Enzymatic Domains |
Flavodoxin-like 539-677 PROSITE-ProRule
FAD-binding FR-type 730-970 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | NOS2 | Ser745 | KSRQNLQsPTSSRAT | phosphorylation up-regulates | 17804409 | SIGNOR-157711 |
| SRC | NOS2 | Tyr151 | IEFVNQYyGSFKEAK | phosphorylation up-regulates | 19875457 | SIGNOR-188974 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | NOS2 PSer745 | phosphorylation up-regulates → | NOS2 | 17804409 | SIGNOR-157711 |
| SRC | phosphorylation up-regulates → | NOS2 PTyr151 | phosphorylation up-regulates → | NOS2 | 19875457 | SIGNOR-188974 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation → up-regulates | NOS2 | SIGNOR-157711 |
| SRC | phosphorylation → up-regulates | NOS2 | SIGNOR-188974 |