Entity Details

Name IGF1R_Tyr989
ID P35568
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
IGF1RIRS1Tyr989VPSSRGDyMTMQMSCphosphorylation
up-regulates		17827393SIGNOR-157758
INSRIRS1Tyr989VPSSRGDyMTMQMSCphosphorylation
up-regulates activity		7651388SIGNOR-235979
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
IGF1Rphosphorylation
up-regulates
→
IRS1
PTyr989		phosphorylation
up-regulates
→		IRS117827393SIGNOR-157758
INSRphosphorylation
up-regulates
→
IRS1
PTyr989		phosphorylation
up-regulates
→		IRS17651388SIGNOR-235979
Regulator Mechanism/Effect Target SIGNOR-ID
IGF1Rphosphorylation
→
up-regulates 		IRS1SIGNOR-157758
INSRphosphorylation
→
up-regulates activity 		IRS1SIGNOR-235979