Entity Details

Name IRS1_Tyr1229
ID P35568
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
INSRIRS1Tyr1229SSEDLSAyASISFQKphosphorylation
up-regulates activity		12220227SIGNOR-235983
IGF1RIRS1Tyr1229SSEDLSAyASISFQKphosphorylation
up-regulates		17827393SIGNOR-157734
INSRIRS1Tyr1229SSEDLSAyASISFQKphosphorylation
up-regulates activity		7651388SIGNOR-236752
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
INSRphosphorylation
up-regulates
→
IRS1
PTyr1229		phosphorylation
up-regulates
→		IRS112220227SIGNOR-235983
IGF1Rphosphorylation
up-regulates
→
IRS1
PTyr1229		phosphorylation
up-regulates
→		IRS117827393SIGNOR-157734
INSRphosphorylation
up-regulates
→
IRS1
PTyr1229		phosphorylation
up-regulates
→		IRS17651388SIGNOR-236752
Regulator Mechanism/Effect Target SIGNOR-ID
INSRphosphorylation
→
up-regulates activity 		IRS1SIGNOR-235983
IGF1Rphosphorylation
→
up-regulates 		IRS1SIGNOR-157734
INSRphosphorylation
→
up-regulates activity 		IRS1SIGNOR-236752