Entity Details

Name MAPK8_Ser636
ID P35568
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK8IRS1Ser636SGDYMPMsPKSVSAPphosphorylation
down-regulates activity		12510059SIGNOR-96948
MAPK3IRS1Ser636SGDYMPMsPKSVSAPphosphorylation
down-regulates activity		12510059SIGNOR-249409
RPS6KB1IRS1Ser636SGDYMPMsPKSVSAPphosphorylation
down-regulates activity		15306821SIGNOR-127912
MAPK1IRS1Ser636SGDYMPMsPKSVSAPphosphorylation
down-regulates activity		12510059SIGNOR-249407
MTORIRS1Ser636SGDYMPMsPKSVSAPphosphorylation
down-regulates activity		11287630SIGNOR-106586
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK8phosphorylation
up-regulates
→
IRS1
PSer636		phosphorylation
down-regulates
⊣		IRS112510059SIGNOR-96948
MAPK3phosphorylation
up-regulates
→
IRS1
PSer636		phosphorylation
down-regulates
⊣		IRS112510059SIGNOR-249409
RPS6KB1phosphorylation
up-regulates
→
IRS1
PSer636		phosphorylation
down-regulates
⊣		IRS115306821SIGNOR-127912
MAPK1phosphorylation
up-regulates
→
IRS1
PSer636		phosphorylation
down-regulates
⊣		IRS112510059SIGNOR-249407
MTORphosphorylation
up-regulates
→
IRS1
PSer636		phosphorylation
down-regulates
⊣		IRS111287630SIGNOR-106586
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK8phosphorylation
→
down-regulates activity 		IRS1SIGNOR-96948
MAPK3phosphorylation
→
down-regulates activity 		IRS1SIGNOR-249409
RPS6KB1phosphorylation
→
down-regulates activity 		IRS1SIGNOR-127912
MAPK1phosphorylation
→
down-regulates activity 		IRS1SIGNOR-249407
MTORphosphorylation
→
down-regulates activity 		IRS1SIGNOR-106586