Entity Details

Name PRKCZ_Ser1101
ID P35568
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCQIRS1Ser1101GCRRRHSsETFSSTPphosphorylation
down-regulates activity		15364919SIGNOR-260906
PRKCDIRS1Ser1101GCRRRHSsETFSSTPphosphorylation
down-regulates activity		15364919SIGNOR-249267
RPS6KB1IRS1Ser1101GCRRRHSsETFSSTPphosphorylation
down-regulates activity		15306821SIGNOR-127904
PRKCZIRS1Ser1101GCRRRHSsETFSSTPphosphorylation
down-regulates quantity by destabilization		17360977SIGNOR-236022
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKCQphosphorylation
up-regulates
→
IRS1
PSer1101		phosphorylation
down-regulates
⊣		IRS115364919SIGNOR-260906
PRKCDphosphorylation
up-regulates
→
IRS1
PSer1101		phosphorylation
down-regulates
⊣		IRS115364919SIGNOR-249267
RPS6KB1phosphorylation
up-regulates
→
IRS1
PSer1101		phosphorylation
down-regulates
⊣		IRS115306821SIGNOR-127904
PRKCZphosphorylation
up-regulates
→
IRS1
PSer1101		phosphorylation
down-regulates
⊣		IRS117360977SIGNOR-236022
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCQphosphorylation
→
down-regulates activity 		IRS1SIGNOR-260906
PRKCDphosphorylation
→
down-regulates activity 		IRS1SIGNOR-249267
RPS6KB1phosphorylation
→
down-regulates activity 		IRS1SIGNOR-127904
PRKCZphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		IRS1SIGNOR-236022