| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| FLT3 | FLT3 | Tyr589 | TGSSDNEyFYVDFRE | phosphorylation up-regulates | 11971190 | SIGNOR-117571 |
| FLT3 | FLT3 | Tyr589 | TGSSDNEyFYVDFRE | phosphorylation up-regulates activity | 16627759 | SIGNOR-271926 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| FLT3 | phosphorylation up-regulates → | FLT3 PTyr589 | phosphorylation up-regulates → | FLT3 | 11971190 | SIGNOR-117571 |
| FLT3 | phosphorylation up-regulates → | FLT3 PTyr589 | phosphorylation up-regulates → | FLT3 | 16627759 | SIGNOR-271926 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| FLT3 | phosphorylation → up-regulates | FLT3 | SIGNOR-117571 |
| FLT3 | phosphorylation → up-regulates activity | FLT3 | SIGNOR-271926 |
