Entity Details

Name PIM1_Tyr591
ID P36888
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
FLT3FLT3Tyr591SSDNEYFyVDFREYEphosphorylation
up-regulates		11971190SIGNOR-117575
FLT3FLT3Tyr591SSDNEYFyVDFREYEphosphorylation
up-regulates activity		16627759SIGNOR-271921
PIM1FLT3Tyr591SSDNEYFyVDFREYEphosphorylation
up-regulates quantity		24040307SIGNOR-259927
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
FLT3phosphorylation
up-regulates
→
FLT3
PTyr591		phosphorylation
up-regulates
→		FLT311971190SIGNOR-117575
FLT3phosphorylation
up-regulates
→
FLT3
PTyr591		phosphorylation
up-regulates
→		FLT316627759SIGNOR-271921
PIM1phosphorylation
up-regulates
→
FLT3
PTyr591		phosphorylation
up-regulates
→		FLT324040307SIGNOR-259927
Regulator Mechanism/Effect Target SIGNOR-ID
FLT3phosphorylation
→
up-regulates 		FLT3SIGNOR-117575
FLT3phosphorylation
→
up-regulates activity 		FLT3SIGNOR-271921
PIM1phosphorylation
→
up-regulates quantity 		FLT3SIGNOR-259927