| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TGFBR2 | TGFBR2 | Ser416 | SVDDLANsGQVGTAR | phosphorylation down-regulates activity | 9155023 | SIGNOR-246737 |
| TGFBR2 | TGFBR2 | Ser416 | SVDDLANsGQVGTAR | phosphorylation down-regulates activity | 9155023 | SIGNOR-48412 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| TGFBR2 | phosphorylation up-regulates → | TGFBR2 PSer416 | phosphorylation down-regulates ⊣ | TGFBR2 | 9155023 | SIGNOR-246737 |
| TGFBR2 | phosphorylation up-regulates → | TGFBR2 PSer416 | phosphorylation down-regulates ⊣ | TGFBR2 | 9155023 | SIGNOR-48412 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| TGFBR2 | phosphorylation → down-regulates activity | TGFBR2 | SIGNOR-246737 |
| TGFBR2 | phosphorylation → down-regulates activity | TGFBR2 | SIGNOR-48412 |