Entity Details

Name CDKN1A_Thr57
ID P38936
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1CDKN1AThr57NFDFVTEtPLEGDFAphosphorylation
down-regulates quantity by destabilization		19364816SIGNOR-185219
MAPK8CDKN1AThr57NFDFVTEtPLEGDFAphosphorylation
up-regulates quantity by stabilization		12058028SIGNOR-250118
ERK1/2CDKN1AThr57NFDFVTEtPLEGDFAphosphorylation
down-regulates quantity by destabilization		19364816SIGNOR-244513
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
CDKN1A
PThr57		phosphorylation
down-regulates
⊣		CDKN1A19364816SIGNOR-185219
MAPK8phosphorylation
up-regulates
→
CDKN1A
PThr57		phosphorylation
up-regulates
→		CDKN1A12058028SIGNOR-250118
ERK1/2phosphorylation
up-regulates
→
CDKN1A
PThr57		phosphorylation
down-regulates
⊣		CDKN1A19364816SIGNOR-244513
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CDKN1ASIGNOR-185219
MAPK8phosphorylation
→
up-regulates quantity by stabilization 		CDKN1ASIGNOR-250118
ERK1/2phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		CDKN1ASIGNOR-244513