| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK3 | STAT3 | Thr622 | KEGGVTFtWVEKDIS | phosphorylation down-regulates activity | 35722967 | SIGNOR-277599 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| STK3 | phosphorylation up-regulates → | STAT3 PThr622 | phosphorylation down-regulates ⊣ | STAT3 | 35722967 | SIGNOR-277599 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| STK3 | phosphorylation → down-regulates activity | STAT3 | SIGNOR-277599 |