Entity Details

Name CCNF
ID P41002
Role substrate
Enzymatic Domains
F-box 29-76
PROSITE-ProRule
Cyclin N-terminal 288-405

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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKTCCNFThr31RRRPRNLtILSLPEDphosphorylation
up-regulates activity		28954236SIGNOR-266360
AKTCCNFSer577TKRKRENsLQEDRGSphosphorylation
up-regulates activity		28954236SIGNOR-266361
CSNK2A1CCNFSer621GYEGDQEsEGEKEGDphosphorylation
down-regulates activity		29021214SIGNOR-266373
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKTphosphorylation
up-regulates
→
CCNF
PThr31		phosphorylation
up-regulates
→		CCNF28954236SIGNOR-266360
AKTphosphorylation
up-regulates
→
CCNF
PSer577		phosphorylation
up-regulates
→		CCNF28954236SIGNOR-266361
CSNK2A1phosphorylation
up-regulates
→
CCNF
PSer621		phosphorylation
down-regulates
⊣		CCNF29021214SIGNOR-266373
Regulator Mechanism/Effect Target SIGNOR-ID
AKTphosphorylation
→
up-regulates activity 		CCNFSIGNOR-266360
AKTphosphorylation
→
up-regulates activity 		CCNFSIGNOR-266361
CSNK2A1phosphorylation
→
down-regulates activity 		CCNFSIGNOR-266373