Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
PRKCI	GLI1	–		phosphorylation up-regulates activity	26343727	SIGNOR-279262
PRKCI	VIM	Ser34	SRSYVTTsTRTYSLG	phosphorylation up-regulates activity	33525953	SIGNOR-277623
PRKCI	MAPT	Ser324	RHLSNVSsTGSIDMV	phosphorylation down-regulates activity	10090741	SIGNOR-275446
PRKCI	EZR	Thr567	QGRDKYKtLRQIRQG	phosphorylation up-regulates	18270268	SIGNOR-160855
PRKCI	NOS3	Thr495	TGITRKKtFKEVANA	phosphorylation down-regulates activity	24379783	SIGNOR-251635
PRKCI	NUMB	–		phosphorylation down-regulates	17609107	SIGNOR-156765
PRKCI	CDK7	Thr170	GSPNRAYtHQVVTRW	phosphorylation up-regulates activity	31784510	SIGNOR-280088
PRKCI	LLGL1	Ser659	RVKSLKKsLRQSFRR	phosphorylation up-regulates activity	12725730	SIGNOR-263179
PRKCI	LLGL2	Ser653	LKKSLRQsFRRMRRS	phosphorylation up-regulates activity	12725730	SIGNOR-263180
PRKCI	BAD	Ser118	GRELRRMsDEFVDSF	phosphorylation down-regulates	21419810	SIGNOR-172886
PRKCI	BAD	Ser75	EIRSRHSsYPAGTED	phosphorylation down-regulates	21419810	SIGNOR-172890
PRKCI	BAD	Ser99	PFRGRSRsAPPNLWA	phosphorylation down-regulates	21419810	SIGNOR-172894
PRKCI	FBXW7	Ser18	KRRRTGGsLRGNPSS	phosphorylation down-regulates activity	28850619	SIGNOR-277250
PRKCI	ECT2	Thr359	YLYEKANtPELKKSV	phosphorylation up-regulates	21189248	SIGNOR-170790
PRKCI	PARD6A	Ser345	RGDGSGFsL	phosphorylation up-regulates quantity by stabilization	23249950	SIGNOR-276432

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
PRKCI	phosphorylation up-regulates →	VIM PSer34	phosphorylation up-regulates →	VIM	33525953	SIGNOR-277623
PRKCI	phosphorylation up-regulates →	MAPT PSer324	phosphorylation down-regulates ⊣	MAPT	10090741	SIGNOR-275446
PRKCI	phosphorylation up-regulates →	EZR PThr567	phosphorylation up-regulates →	EZR	18270268	SIGNOR-160855
PRKCI	phosphorylation up-regulates →	NOS3 PThr495	phosphorylation down-regulates ⊣	NOS3	24379783	SIGNOR-251635
PRKCI	phosphorylation up-regulates →	CDK7 PThr170	phosphorylation up-regulates →	CDK7	31784510	SIGNOR-280088
PRKCI	phosphorylation up-regulates →	LLGL1 PSer659	phosphorylation up-regulates →	LLGL1	12725730	SIGNOR-263179
PRKCI	phosphorylation up-regulates →	LLGL2 PSer653	phosphorylation up-regulates →	LLGL2	12725730	SIGNOR-263180
PRKCI	phosphorylation up-regulates →	BAD PSer118	phosphorylation down-regulates ⊣	BAD	21419810	SIGNOR-172886
PRKCI	phosphorylation up-regulates →	BAD PSer75	phosphorylation down-regulates ⊣	BAD	21419810	SIGNOR-172890
PRKCI	phosphorylation up-regulates →	BAD PSer99	phosphorylation down-regulates ⊣	BAD	21419810	SIGNOR-172894
PRKCI	phosphorylation up-regulates →	FBXW7 PSer18	phosphorylation down-regulates ⊣	FBXW7	28850619	SIGNOR-277250
PRKCI	phosphorylation up-regulates →	ECT2 PThr359	phosphorylation up-regulates →	ECT2	21189248	SIGNOR-170790
PRKCI	phosphorylation up-regulates →	PARD6A PSer345	phosphorylation up-regulates →	PARD6A	23249950	SIGNOR-276432

Regulator	Mechanism/Effect	Target	SIGNOR-ID
PRKCI	phosphorylation → up-regulates activity	GLI1	SIGNOR-279262
PRKCI	phosphorylation → up-regulates activity	VIM	SIGNOR-277623
PRKCI	phosphorylation → down-regulates activity	MAPT	SIGNOR-275446
PRKCI	phosphorylation → up-regulates	EZR	SIGNOR-160855
PRKCI	phosphorylation → down-regulates activity	NOS3	SIGNOR-251635
PRKCI	phosphorylation down-regulates	NUMB	SIGNOR-156765
PRKCI	phosphorylation → up-regulates activity	CDK7	SIGNOR-280088
PRKCI	phosphorylation → up-regulates activity	LLGL1	SIGNOR-263179
PRKCI	phosphorylation → up-regulates activity	LLGL2	SIGNOR-263180
PRKCI	phosphorylation down-regulates	BAD	SIGNOR-172886
PRKCI	phosphorylation down-regulates	BAD	SIGNOR-172890
PRKCI	phosphorylation down-regulates	BAD	SIGNOR-172894
PRKCI	phosphorylation → down-regulates activity	FBXW7	SIGNOR-277250
PRKCI	phosphorylation → up-regulates	ECT2	SIGNOR-170790
PRKCI	phosphorylation → up-regulates quantity by stabilization	PARD6A	SIGNOR-276432