| Name | PRKCI |
| ID | P41743 |
| Role | substrate |
| Enzymatic Domains |
PB1 25-108 PROSITE-ProRule
Protein kinase 254-522 PROSITE-ProRule
AGC-kinase C-terminal 523-594 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | PRKCI | Tyr280 | LKKTDRIyAMKVVKK | phosphorylation up-regulates | 11713277 | SIGNOR-111924 |
| SRC | PRKCI | Tyr334 | RLFFVIEyVNGGDLM | phosphorylation up-regulates | 11713277 | SIGNOR-111928 |
| SRC | PRKCI | Tyr265 | RVIGRGSyAKVLLVR | phosphorylation up-regulates | 11713277 | SIGNOR-111920 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | PRKCI PTyr280 | phosphorylation up-regulates → | PRKCI | 11713277 | SIGNOR-111924 |
| SRC | phosphorylation up-regulates → | PRKCI PTyr334 | phosphorylation up-regulates → | PRKCI | 11713277 | SIGNOR-111928 |
| SRC | phosphorylation up-regulates → | PRKCI PTyr265 | phosphorylation up-regulates → | PRKCI | 11713277 | SIGNOR-111920 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → up-regulates | PRKCI | SIGNOR-111924 |
| SRC | phosphorylation → up-regulates | PRKCI | SIGNOR-111928 |
| SRC | phosphorylation → up-regulates | PRKCI | SIGNOR-111920 |