| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PTPN5 | GRIA2 | – | dephosphorylation down-regulates activity | 21883219 | SIGNOR-277040 | |
| PRKCA | GRIA2 | Ser717 | GVARVRKsKGKYAYL | phosphorylation unknown | 8848293 | SIGNOR-248955 |
| PRKCA | GRIA2 | Ser683 | TKEFFRRsKIAVFDK | phosphorylation unknown | 8848293 | SIGNOR-248954 |
| PRKCA | GRIA2 | Ser880 | YNVYGIEsVKI | phosphorylation unknown | 10501226 | SIGNOR-249022 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCA | phosphorylation up-regulates → | GRIA2 PSer717 | phosphorylation down-regulates ⊣ | GRIA2 | 8848293 | SIGNOR-248955 |
| PRKCA | phosphorylation up-regulates → | GRIA2 PSer683 | phosphorylation down-regulates ⊣ | GRIA2 | 8848293 | SIGNOR-248954 |
| PRKCA | phosphorylation up-regulates → | GRIA2 PSer880 | phosphorylation down-regulates ⊣ | GRIA2 | 10501226 | SIGNOR-249022 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PTPN5 | dephosphorylation → down-regulates activity | GRIA2 | SIGNOR-277040 |
| PRKCA | phosphorylation → unknown | GRIA2 | SIGNOR-248955 |
| PRKCA | phosphorylation → unknown | GRIA2 | SIGNOR-248954 |
| PRKCA | phosphorylation → unknown | GRIA2 | SIGNOR-249022 |
