Entity Details

Name MAP4K4_Thr1061
ID P42336
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
STK3PIK3CAThr1061KMDWIFHtIKQHALNphosphorylation
down-regulates activity		38060450SIGNOR-277922
MAP4K4PIK3CAThr1061KMDWIFHtIKQHALNphosphorylation
down-regulates activity		38060450SIGNOR-277921
STK4PIK3CAThr1061KMDWIFHtIKQHALNphosphorylation
down-regulates activity		38060450SIGNOR-277920
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
STK3phosphorylation
up-regulates
→
PIK3CA
PThr1061		phosphorylation
down-regulates
⊣		PIK3CA38060450SIGNOR-277922
MAP4K4phosphorylation
up-regulates
→
PIK3CA
PThr1061		phosphorylation
down-regulates
⊣		PIK3CA38060450SIGNOR-277921
STK4phosphorylation
up-regulates
→
PIK3CA
PThr1061		phosphorylation
down-regulates
⊣		PIK3CA38060450SIGNOR-277920
Regulator Mechanism/Effect Target SIGNOR-ID
STK3phosphorylation
→
down-regulates activity 		PIK3CASIGNOR-277922
MAP4K4phosphorylation
→
down-regulates activity 		PIK3CASIGNOR-277921
STK4phosphorylation
→
down-regulates activity 		PIK3CASIGNOR-277920