Entity Details

Name AKT_Ser80
ID P45985
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKTMAP2K4Ser80IERLRTHsIESSGKLphosphorylation
down-regulates activity		11707464SIGNOR-275980
AKTMAP2K4Ser80IERLRTHsIESSGKLphosphorylation
down-regulates		11707464SIGNOR-244285
AKT1MAP2K4Ser80IERLRTHsIESSGKLphosphorylation
down-regulates		11707464SIGNOR-236494
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKTphosphorylation
up-regulates
→
MAP2K4
PSer80		phosphorylation
down-regulates
⊣		MAP2K411707464SIGNOR-275980
AKTphosphorylation
up-regulates
→
MAP2K4
PSer80		phosphorylation
down-regulates
⊣		MAP2K411707464SIGNOR-244285
AKT1phosphorylation
up-regulates
→
MAP2K4
PSer80		phosphorylation
down-regulates
⊣		MAP2K411707464SIGNOR-236494
Regulator Mechanism/Effect Target SIGNOR-ID
AKTphosphorylation
→
down-regulates activity 		MAP2K4SIGNOR-275980
AKTphosphorylation
img/direct_inhibition.png
down-regulates 		MAP2K4SIGNOR-244285
AKT1phosphorylation
img/direct_inhibition.png
down-regulates 		MAP2K4SIGNOR-236494