Entity Details

Name JAK2_Tyr986
ID P48357
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
JAK2LEPRTyr986QRQPFVKyATLISNSphosphorylation
up-regulates activity		11018044SIGNOR-263493
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
JAK2phosphorylation
up-regulates
→
LEPR
PTyr986		phosphorylation
up-regulates
→		LEPR11018044SIGNOR-263493
Regulator Mechanism/Effect Target SIGNOR-ID
JAK2phosphorylation
→
up-regulates activity 		LEPRSIGNOR-263493