Entity Details

Name MAPK3_Ser251
ID P48431
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK2SOX2Ser251VKSEASSsPPVVTSSphosphorylation
up-regulates activity		26139602SIGNOR-279449
MAPK3SOX2Ser251VKSEASSsPPVVTSSphosphorylation
down-regulates activity		29556337SIGNOR-279071
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK2phosphorylation
up-regulates
→
SOX2
PSer251		phosphorylation
up-regulates
→		SOX226139602SIGNOR-279449
MAPK3phosphorylation
up-regulates
→
SOX2
PSer251		phosphorylation
down-regulates
⊣		SOX229556337SIGNOR-279071
Regulator Mechanism/Effect Target SIGNOR-ID
CDK2phosphorylation
→
up-regulates activity 		SOX2SIGNOR-279449
MAPK3phosphorylation
→
down-regulates activity 		SOX2SIGNOR-279071