Entity Details

Name CEBPA
ID P49715
Role substrate
Enzymatic Domains
bZIP 282-345
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKCDCEBPASer21PMSSHLQsPPHAPSSphosphorylation
down-regulates quantity by destabilization
23814099SIGNOR-279427
GSK3BCEBPAThr230GHPTPPPtPVPSPHPphosphorylation
up-regulates activity
10567568SIGNOR-251232
PCSK7CEBPAphosphorylation
down-regulates
19544470SIGNOR-186202
PRKCDCEBPAphosphorylation
down-regulates quantity by destabilization
23473759SIGNOR-279426
MAPK3CEBPASer21PMSSHLQsPPHAPSSphosphorylation
down-regulates
14701740SIGNOR-120570
GbetaCEBPAphosphorylation
down-regulates
14701740SIGNOR-270066
MAPK1CEBPASer21PMSSHLQsPPHAPSSphosphorylation
down-regulates
14701740SIGNOR-120566
GSK3BCEBPAThr226HLQPGHPtPPPTPVPphosphorylation
up-regulates activity
10567568SIGNOR-251231
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKCDphosphorylation
up-regulates
CEBPA
PSer21
phosphorylation
down-regulates
CEBPA23814099SIGNOR-279427
GSK3Bphosphorylation
up-regulates
CEBPA
PThr230
phosphorylation
up-regulates
CEBPA10567568SIGNOR-251232
MAPK3phosphorylation
up-regulates
CEBPA
PSer21
phosphorylation
down-regulates
CEBPA14701740SIGNOR-120570
MAPK1phosphorylation
up-regulates
CEBPA
PSer21
phosphorylation
down-regulates
CEBPA14701740SIGNOR-120566
GSK3Bphosphorylation
up-regulates
CEBPA
PThr226
phosphorylation
up-regulates
CEBPA10567568SIGNOR-251231
Regulator Mechanism/Effect Target SIGNOR-ID
PRKCDphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
CEBPASIGNOR-279427
GSK3Bphosphorylation

up-regulates activity
CEBPASIGNOR-251232
PCSK7phosphorylation
img/direct_inhibition.png
down-regulates
CEBPASIGNOR-186202
PRKCDphosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
CEBPASIGNOR-279426
MAPK3phosphorylation
img/direct_inhibition.png
down-regulates
CEBPASIGNOR-120570
Gbetaphosphorylation
img/direct_inhibition.png
down-regulates
CEBPASIGNOR-270066
MAPK1phosphorylation
img/direct_inhibition.png
down-regulates
CEBPASIGNOR-120566
GSK3Bphosphorylation

up-regulates activity
CEBPASIGNOR-251231