| Name | CEBPA |
| ID | P49715 |
| Role | substrate |
| Enzymatic Domains |
bZIP 282-345 PROSITE-ProRule |
View in ![]() |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | CEBPA | Ser21 | PMSSHLQsPPHAPSS | phosphorylation down-regulates quantity by destabilization | 23814099 | SIGNOR-279427 |
| GSK3B | CEBPA | Thr230 | GHPTPPPtPVPSPHP | phosphorylation up-regulates activity | 10567568 | SIGNOR-251232 |
| PCSK7 | CEBPA | – | phosphorylation down-regulates | 19544470 | SIGNOR-186202 | |
| PRKCD | CEBPA | – | phosphorylation down-regulates quantity by destabilization | 23473759 | SIGNOR-279426 | |
| MAPK3 | CEBPA | Ser21 | PMSSHLQsPPHAPSS | phosphorylation down-regulates | 14701740 | SIGNOR-120570 |
| Gbeta | CEBPA | – | phosphorylation down-regulates | 14701740 | SIGNOR-270066 | |
| MAPK1 | CEBPA | Ser21 | PMSSHLQsPPHAPSS | phosphorylation down-regulates | 14701740 | SIGNOR-120566 |
| GSK3B | CEBPA | Thr226 | HLQPGHPtPPPTPVP | phosphorylation up-regulates activity | 10567568 | SIGNOR-251231 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | phosphorylation up-regulates → | CEBPA PSer21 | phosphorylation down-regulates ⊣ | CEBPA | 23814099 | SIGNOR-279427 |
| GSK3B | phosphorylation up-regulates → | CEBPA PThr230 | phosphorylation up-regulates → | CEBPA | 10567568 | SIGNOR-251232 |
| MAPK3 | phosphorylation up-regulates → | CEBPA PSer21 | phosphorylation down-regulates ⊣ | CEBPA | 14701740 | SIGNOR-120570 |
| MAPK1 | phosphorylation up-regulates → | CEBPA PSer21 | phosphorylation down-regulates ⊣ | CEBPA | 14701740 | SIGNOR-120566 |
| GSK3B | phosphorylation up-regulates → | CEBPA PThr226 | phosphorylation up-regulates → | CEBPA | 10567568 | SIGNOR-251231 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCD | phosphorylation![]() down-regulates quantity by destabilization | CEBPA | SIGNOR-279427 |
| GSK3B | phosphorylation → up-regulates activity | CEBPA | SIGNOR-251232 |
| PCSK7 | phosphorylation![]() down-regulates | CEBPA | SIGNOR-186202 |
| PRKCD | phosphorylation![]() down-regulates quantity by destabilization | CEBPA | SIGNOR-279426 |
| MAPK3 | phosphorylation![]() down-regulates | CEBPA | SIGNOR-120570 |
| Gbeta | phosphorylation![]() down-regulates | CEBPA | SIGNOR-270066 |
| MAPK1 | phosphorylation![]() down-regulates | CEBPA | SIGNOR-120566 |
| GSK3B | phosphorylation → up-regulates activity | CEBPA | SIGNOR-251231 |