| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | CEBPA | Ser21 | PMSSHLQsPPHAPSS | phosphorylation down-regulates quantity by destabilization | 23814099 | SIGNOR-279427 |
| MAPK3 | CEBPA | Ser21 | PMSSHLQsPPHAPSS | phosphorylation down-regulates | 14701740 | SIGNOR-120570 |
| MAPK1 | CEBPA | Ser21 | PMSSHLQsPPHAPSS | phosphorylation down-regulates | 14701740 | SIGNOR-120566 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCD | phosphorylation up-regulates → | CEBPA PSer21 | phosphorylation down-regulates ⊣ | CEBPA | 23814099 | SIGNOR-279427 |
| MAPK3 | phosphorylation up-regulates → | CEBPA PSer21 | phosphorylation down-regulates ⊣ | CEBPA | 14701740 | SIGNOR-120570 |
| MAPK1 | phosphorylation up-regulates → | CEBPA PSer21 | phosphorylation down-regulates ⊣ | CEBPA | 14701740 | SIGNOR-120566 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCD | phosphorylation down-regulates quantity by destabilization | CEBPA | SIGNOR-279427 |
| MAPK3 | phosphorylation down-regulates | CEBPA | SIGNOR-120570 |
| MAPK1 | phosphorylation down-regulates | CEBPA | SIGNOR-120566 |
