| Name | LIG4 |
| ID | P49917 |
| Role | substrate |
| Enzymatic Domains |
BRCT 1 654-743 PROSITE-ProRule
BRCT 2 808-911 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKDC | LIG4 | Ser668 | DVEFCVMsGTDSQPK | phosphorylation down-regulates | 15194694 | SIGNOR-125869 |
| PRKDC | LIG4 | Ser672 | CVMSGTDsQPKPDLE | phosphorylation down-regulates | 15194694 | SIGNOR-125873 |
| PRKDC | LIG4 | Thr650 | HLKAPNLtNVNKISN | phosphorylation down-regulates | 15194694 | SIGNOR-125877 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKDC | phosphorylation up-regulates → | LIG4 PSer668 | phosphorylation down-regulates ⊣ | LIG4 | 15194694 | SIGNOR-125869 |
| PRKDC | phosphorylation up-regulates → | LIG4 PSer672 | phosphorylation down-regulates ⊣ | LIG4 | 15194694 | SIGNOR-125873 |
| PRKDC | phosphorylation up-regulates → | LIG4 PThr650 | phosphorylation down-regulates ⊣ | LIG4 | 15194694 | SIGNOR-125877 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKDC | phosphorylation down-regulates | LIG4 | SIGNOR-125869 |
| PRKDC | phosphorylation down-regulates | LIG4 | SIGNOR-125873 |
| PRKDC | phosphorylation down-regulates | LIG4 | SIGNOR-125877 |