| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinA2/CDK2 | CDK7 | Ser164 | GLAKSFGsPNRAYTH | phosphorylation up-regulates activity | 11113184 | SIGNOR-270807 |
| CDK2 | CDK7 | Ser164 | GLAKSFGsPNRAYTH | phosphorylation unknown | 11113184 | SIGNOR-84832 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinA2/CDK2 | phosphorylation up-regulates → | CDK7 PSer164 | phosphorylation up-regulates → | CDK7 | 11113184 | SIGNOR-270807 |
| CDK2 | phosphorylation up-regulates → | CDK7 PSer164 | phosphorylation down-regulates ⊣ | CDK7 | 11113184 | SIGNOR-84832 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinA2/CDK2 | phosphorylation → up-regulates activity | CDK7 | SIGNOR-270807 |
| CDK2 | phosphorylation → unknown | CDK7 | SIGNOR-84832 |
