| Name | MECP2 |
| ID | P51608 |
| Role | substrate |
| Enzymatic Domains |
MBD 90-162 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDKL5 | MECP2 | – | phosphorylation unknown | 16935860 | SIGNOR-264702 | |
| HIPK2 | MECP2 | Ser80 | AVPEASAsPKQRRSI | phosphorylation up-regulates activity | 19820693 | SIGNOR-264549 |
| CHUK | MECP2 | Ser423 | EKMPRGGsLESDGCP | phosphorylation up-regulates activity | 22848609 | SIGNOR-279459 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HIPK2 | phosphorylation up-regulates → | MECP2 PSer80 | phosphorylation up-regulates → | MECP2 | 19820693 | SIGNOR-264549 |
| CHUK | phosphorylation up-regulates → | MECP2 PSer423 | phosphorylation up-regulates → | MECP2 | 22848609 | SIGNOR-279459 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDKL5 | phosphorylation → unknown | MECP2 | SIGNOR-264702 |
| HIPK2 | phosphorylation → up-regulates activity | MECP2 | SIGNOR-264549 |
| CHUK | phosphorylation → up-regulates activity | MECP2 | SIGNOR-279459 |