| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HIPK2 | MECP2 | Ser80 | AVPEASAsPKQRRSI | phosphorylation up-regulates activity | 19820693 | SIGNOR-264549 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| HIPK2 | phosphorylation up-regulates → | MECP2 PSer80 | phosphorylation up-regulates → | MECP2 | 19820693 | SIGNOR-264549 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| HIPK2 | phosphorylation → up-regulates activity | MECP2 | SIGNOR-264549 |
