Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
NEK7	KIF11	Ser1033	GINTLERsKVEETTE	phosphorylation up-regulates activity	29899413	SIGNOR-273890
PTEN	KIF11	Thr926 View in OncoXplorer	LDIPTGTtPQRKSYL	dephosphorylation up-regulates activity	27492783	SIGNOR-277000
CDK1	KIF11	Thr926 View in OncoXplorer	LDIPTGTtPQRKSYL	phosphorylation up-regulates activity	19001501	SIGNOR-273887
NEK6	KIF11	Ser1033	GINTLERsKVEETTE	phosphorylation up-regulates activity	19001501	SIGNOR-273886
CDK1	KIF11	Thr926 View in OncoXplorer	LDIPTGTtPQRKSYL	phosphorylation up-regulates	9235942	SIGNOR-50169

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
NEK7	phosphorylation up-regulates →	KIF11 PSer1033	phosphorylation up-regulates →	KIF11	29899413	SIGNOR-273890
PTEN	dephosphorylation down-regulates ⊣	KIF11 PThr926	dephosphorylation down-regulates ⊣	KIF11	27492783	SIGNOR-277000
CDK1	phosphorylation up-regulates →	KIF11 PThr926	phosphorylation up-regulates →	KIF11	19001501	SIGNOR-273887
NEK6	phosphorylation up-regulates →	KIF11 PSer1033	phosphorylation up-regulates →	KIF11	19001501	SIGNOR-273886
CDK1	phosphorylation up-regulates →	KIF11 PThr926	phosphorylation up-regulates →	KIF11	9235942	SIGNOR-50169

Regulator	Mechanism/Effect	Target	SIGNOR-ID
NEK7	phosphorylation → up-regulates activity	KIF11	SIGNOR-273890
PTEN	dephosphorylation → up-regulates activity	KIF11	SIGNOR-277000
CDK1	phosphorylation → up-regulates activity	KIF11	SIGNOR-273887
NEK6	phosphorylation → up-regulates activity	KIF11	SIGNOR-273886
CDK1	phosphorylation → up-regulates	KIF11	SIGNOR-50169