Summary

Name KIF11
Full Name Kinesin-like protein KIF11
Synonyms Kinesin-like protein 1, Kinesin-like spindle protein HKSP, Kinesin-related motor protein Eg5, Thyroid receptor-interacting protein 5, TR-interacting protein 5, TRIP-5 | EG5, KNSL1, TRIP5
Primary ID P52732
Links - -
Type protein
Relations 4
Inhibitors ARRY-520; Ispinesib; 940929-33-9
Function Motor protein required for establishing a bipolar spindle during mitosis (PubMed:19001501). Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface (PubMed:23857769).

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation KIF11 0.22
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition KIF11 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition KIF11 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png chemical inhibition KIF11 0.14
Publications: 1 Organism: Homo Sapiens