Entity Details

Name CHEK1_Thr539
ID P53350
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CHEK1PLK1Thr539INFFQDHtKLILCPLphosphorylation
down-regulates activity		37596441SIGNOR-277914
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CHEK1phosphorylation
up-regulates
→
PLK1
PThr539		phosphorylation
down-regulates
⊣		PLK137596441SIGNOR-277914
Regulator Mechanism/Effect Target SIGNOR-ID
CHEK1phosphorylation
→
down-regulates activity 		PLK1SIGNOR-277914