| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | PLK1 | Ser49 | EVLVDPRsRRRYVRG | phosphorylation up-regulates | 18427546 | SIGNOR-178353 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PAK1 | phosphorylation up-regulates → | PLK1 PSer49 | phosphorylation up-regulates → | PLK1 | 18427546 | SIGNOR-178353 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PAK1 | phosphorylation → up-regulates | PLK1 | SIGNOR-178353 |