| Name | MAPK10 |
| ID | P53779 |
| Role | substrate |
| Enzymatic Domains |
Protein kinase 64-359 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP2K4 | MAPK10 | – | phosphorylation up-regulates | 10715136 | SIGNOR-75792 | |
| MAP2K4 | MAPK10 | – | phosphorylation up-regulates | 11242034 | SIGNOR-105692 | |
| MAP2K7 | MAPK10 | Thr221 | AGTSFMMtPYVVTRY | phosphorylation up-regulates activity | 10715136 | SIGNOR-251422 |
| MAP2K6 | MAPK10 | – | phosphorylation up-regulates | 8974401 | SIGNOR-45363 | |
| MAP2K7 | MAPK10 | – | phosphorylation up-regulates | 9890973 | SIGNOR-63972 | |
| IL1R1 | MAPK10 | – | phosphorylation up-regulates activity | 9625767 | SIGNOR-249515 | |
| MAP2K4 | MAPK10 | Thr221 | AGTSFMMtPYVVTRY | phosphorylation up-regulates | 17761173 | SIGNOR-260614 |
| MAP2K7 | MAPK10 | – | phosphorylation up-regulates | 11062067 | SIGNOR-83732 | |
| MAP2K7 | MAPK10 | Thr221 | AGTSFMMtPYVVTRY | phosphorylation up-regulates | 15911620 | SIGNOR-137609 |
| MAP2K4 | MAPK10 | – | phosphorylation up-regulates | 8974401 | SIGNOR-45360 | |
| CDK5 | MAPK10 | Thr131 | ISLLNVFtPQKTLEE | phosphorylation down-regulates activity | 11823425 | SIGNOR-250668 |
| MAP2K4 | MAPK10 | – | phosphorylation up-regulates | 11062067 | SIGNOR-83721 | |
| MAP2K4 | MAPK10 | Tyr223 | TSFMMTPyVVTRYYR | phosphorylation up-regulates activity | 10715136 | SIGNOR-251423 |
| MAP2K4 | MAPK10 | Tyr223 | TSFMMTPyVVTRYYR | phosphorylation up-regulates | 15911620 | SIGNOR-137605 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAP2K7 | phosphorylation up-regulates → | MAPK10 PThr221 | phosphorylation up-regulates → | MAPK10 | 10715136 | SIGNOR-251422 |
| MAP2K4 | phosphorylation up-regulates → | MAPK10 PThr221 | phosphorylation up-regulates → | MAPK10 | 17761173 | SIGNOR-260614 |
| MAP2K7 | phosphorylation up-regulates → | MAPK10 PThr221 | phosphorylation up-regulates → | MAPK10 | 15911620 | SIGNOR-137609 |
| CDK5 | phosphorylation up-regulates → | MAPK10 PThr131 | phosphorylation down-regulates ⊣ | MAPK10 | 11823425 | SIGNOR-250668 |
| MAP2K4 | phosphorylation up-regulates → | MAPK10 PTyr223 | phosphorylation up-regulates → | MAPK10 | 10715136 | SIGNOR-251423 |
| MAP2K4 | phosphorylation up-regulates → | MAPK10 PTyr223 | phosphorylation up-regulates → | MAPK10 | 15911620 | SIGNOR-137605 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAP2K4 | phosphorylation → up-regulates | MAPK10 | SIGNOR-75792 |
| MAP2K4 | phosphorylation → up-regulates | MAPK10 | SIGNOR-105692 |
| MAP2K7 | phosphorylation → up-regulates activity | MAPK10 | SIGNOR-251422 |
| MAP2K6 | phosphorylation → up-regulates | MAPK10 | SIGNOR-45363 |
| MAP2K7 | phosphorylation → up-regulates | MAPK10 | SIGNOR-63972 |
| IL1R1 | phosphorylation → up-regulates activity | MAPK10 | SIGNOR-249515 |
| MAP2K4 | phosphorylation → up-regulates | MAPK10 | SIGNOR-260614 |
| MAP2K7 | phosphorylation → up-regulates | MAPK10 | SIGNOR-83732 |
| MAP2K7 | phosphorylation → up-regulates | MAPK10 | SIGNOR-137609 |
| MAP2K4 | phosphorylation → up-regulates | MAPK10 | SIGNOR-45360 |
| CDK5 | phosphorylation → down-regulates activity | MAPK10 | SIGNOR-250668 |
| MAP2K4 | phosphorylation → up-regulates | MAPK10 | SIGNOR-83721 |
| MAP2K4 | phosphorylation → up-regulates activity | MAPK10 | SIGNOR-251423 |
| MAP2K4 | phosphorylation → up-regulates | MAPK10 | SIGNOR-137605 |