Entity Details

Name HIRA
ID P54198
Role substrate
Enzymatic Domains
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK2HIRAThr555
View in OncoXplorer
LSPSVLTtPSKIEPMphosphorylation
up-regulates activity		11238922SIGNOR-105548
AKT1HIRA–phosphorylation
up-regulates activity		27515126SIGNOR-279584
CyclinE/CDK2HIRAThr555
View in OncoXplorer
LSPSVLTtPSKIEPMphosphorylation
up-regulates		11238922SIGNOR-216670
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK2phosphorylation
up-regulates
→
HIRA
PThr555		phosphorylation
up-regulates
→		HIRA11238922SIGNOR-105548
CyclinE/CDK2phosphorylation
up-regulates
→
HIRA
PThr555		phosphorylation
up-regulates
→		HIRA11238922SIGNOR-216670
Regulator Mechanism/Effect Target SIGNOR-ID
CDK2phosphorylation
→
up-regulates activity 		HIRASIGNOR-105548
AKT1phosphorylation
→
up-regulates activity 		HIRASIGNOR-279584
CyclinE/CDK2phosphorylation
→
up-regulates 		HIRASIGNOR-216670