| Name | TERF1 |
| ID | P54274 |
| Role | substrate |
| Enzymatic Domains |
HTH myb-type 375-432 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | TERF1 | Ser435 | KKLKLISsDSED | phosphorylation up-regulates | 18625707 | SIGNOR-179461 |
| NEK7 | TERF1 | Ser114 | AIIHGLSsLTACQLR | phosphorylation up-regulates quantity | 28216227 | SIGNOR-278448 |
| AURKB | TERF1 | Ser404 | KYGEGNWsKILLHYK | phosphorylation up-regulates activity | 29040668 | SIGNOR-279440 |
| NEK7 | TERF1 | Ser114 | AIIHGLSsLTACQLR | phosphorylation up-regulates activity | 28216227 | SIGNOR-278447 |
| NEK7 | TERF1 | Ser114 | AIIHGLSsLTACQLR | phosphorylation up-regulates quantity by stabilization | 28216227 | SIGNOR-273903 |
| CSNK2A1 | TERF1 | Thr122 | LTACQLRtIYICQFL | phosphorylation up-regulates | 18347021 | SIGNOR-178034 |
| ATM | TERF1 | Ser219 | SKLLMIIsQKDTFHS | phosphorylation up-regulates activity | 11375976 | SIGNOR-108419 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PLK1 | phosphorylation up-regulates → | TERF1 PSer435 | phosphorylation up-regulates → | TERF1 | 18625707 | SIGNOR-179461 |
| NEK7 | phosphorylation up-regulates → | TERF1 PSer114 | phosphorylation up-regulates → | TERF1 | 28216227 | SIGNOR-278448 |
| AURKB | phosphorylation up-regulates → | TERF1 PSer404 | phosphorylation up-regulates → | TERF1 | 29040668 | SIGNOR-279440 |
| NEK7 | phosphorylation up-regulates → | TERF1 PSer114 | phosphorylation up-regulates → | TERF1 | 28216227 | SIGNOR-278447 |
| NEK7 | phosphorylation up-regulates → | TERF1 PSer114 | phosphorylation up-regulates → | TERF1 | 28216227 | SIGNOR-273903 |
| CSNK2A1 | phosphorylation up-regulates → | TERF1 PThr122 | phosphorylation up-regulates → | TERF1 | 18347021 | SIGNOR-178034 |
| ATM | phosphorylation up-regulates → | TERF1 PSer219 | phosphorylation up-regulates → | TERF1 | 11375976 | SIGNOR-108419 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PLK1 | phosphorylation → up-regulates | TERF1 | SIGNOR-179461 |
| NEK7 | phosphorylation → up-regulates quantity | TERF1 | SIGNOR-278448 |
| AURKB | phosphorylation → up-regulates activity | TERF1 | SIGNOR-279440 |
| NEK7 | phosphorylation → up-regulates activity | TERF1 | SIGNOR-278447 |
| NEK7 | phosphorylation → up-regulates quantity by stabilization | TERF1 | SIGNOR-273903 |
| CSNK2A1 | phosphorylation → up-regulates | TERF1 | SIGNOR-178034 |
| ATM | phosphorylation → up-regulates activity | TERF1 | SIGNOR-108419 |