Entity Details

Name EPHB1
ID P54762
Role kinase
Enzymatic Domains
Eph LBD 19-201
PROSITE-ProRule
Fibronectin type-III 1 322-432
PROSITE-ProRule
Fibronectin type-III 2 433-528
PROSITE-ProRule
Protein kinase 619-882
PROSITE-ProRule
SAM 911-975
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
EPHB1STAT3phosphorylation
up-regulates activity
29079839SIGNOR-279709
EPHB1EPHB1Tyr594GSPGMKIyIDPFTYEphosphorylation
up-regulates activity
12223469SIGNOR-251122
EPHB1EPHB1Tyr928SAIKMVQyRDSFLTAphosphorylation
up-regulates activity
12223469SIGNOR-251123
EPHB1CAV1Tyr14VDSEGHLyTVPIREQphosphorylation
down-regulates quantity by destabilization
32238105SIGNOR-280008
EPHB1CASKIN1Tyr296TKDYCNNyDLTSLNVphosphorylation
up-regulates activity
23181695SIGNOR-262860
EPHB1CASKIN1Tyr336TGNDRVGyFPSSLGEphosphorylation
up-regulates activity
23181695SIGNOR-262861
EPHB1NRCAMTyr1276DGSFIGQySGKKEKEphosphorylation
up-regulates activity
24023801SIGNOR-262862
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
EPHB1phosphorylation
up-regulates
EPHB1
PTyr594
phosphorylation
up-regulates
EPHB112223469SIGNOR-251122
EPHB1phosphorylation
up-regulates
EPHB1
PTyr928
phosphorylation
up-regulates
EPHB112223469SIGNOR-251123
EPHB1phosphorylation
up-regulates
CAV1
PTyr14
phosphorylation
down-regulates
CAV132238105SIGNOR-280008
EPHB1phosphorylation
up-regulates
CASKIN1
PTyr296
phosphorylation
up-regulates
CASKIN123181695SIGNOR-262860
EPHB1phosphorylation
up-regulates
CASKIN1
PTyr336
phosphorylation
up-regulates
CASKIN123181695SIGNOR-262861
EPHB1phosphorylation
up-regulates
NRCAM
PTyr1276
phosphorylation
up-regulates
NRCAM24023801SIGNOR-262862
Regulator Mechanism/Effect Target SIGNOR-ID
EPHB1phosphorylation

up-regulates activity
STAT3SIGNOR-279709
EPHB1phosphorylation

up-regulates activity
EPHB1SIGNOR-251122
EPHB1phosphorylation

up-regulates activity
EPHB1SIGNOR-251123
EPHB1phosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization
CAV1SIGNOR-280008
EPHB1phosphorylation

up-regulates activity
CASKIN1SIGNOR-262860
EPHB1phosphorylation

up-regulates activity
CASKIN1SIGNOR-262861
EPHB1phosphorylation

up-regulates activity
NRCAMSIGNOR-262862