Entity Details

Name CDK5_Thr252
ID P56817
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK5BACE1Thr252YTGSLWYtPIRREWYphosphorylation
up-regulates activity		26317805SIGNOR-278249
CDK5/CDK5R1BACE1Thr252YTGSLWYtPIRREWYphosphorylation
up-regulates activity		26317805SIGNOR-276934
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK5phosphorylation
up-regulates
→
BACE1
PThr252		phosphorylation
up-regulates
→		BACE126317805SIGNOR-278249
CDK5/CDK5R1phosphorylation
up-regulates
→
BACE1
PThr252		phosphorylation
up-regulates
→		BACE126317805SIGNOR-276934
Regulator Mechanism/Effect Target SIGNOR-ID
CDK5phosphorylation
→
up-regulates activity 		BACE1SIGNOR-278249
CDK5/CDK5R1phosphorylation
→
up-regulates activity 		BACE1SIGNOR-276934