Entity Details

Name BCR-ABL_Tyr34
ID P61586
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
BCR-ABLRHOATyr34KDQFPEVyVPTVFENphosphorylation
down-regulates activity		23027962SIGNOR-271700
SRCRHOATyr34KDQFPEVyVPTVFENphosphorylation
down-regulates activity		23027962SIGNOR-271702
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
BCR-ABLphosphorylation
up-regulates
→
RHOA
PTyr34		phosphorylation
down-regulates
⊣		RHOA23027962SIGNOR-271700
SRCphosphorylation
up-regulates
→
RHOA
PTyr34		phosphorylation
down-regulates
⊣		RHOA23027962SIGNOR-271702
Regulator Mechanism/Effect Target SIGNOR-ID
BCR-ABLphosphorylation
→
down-regulates activity 		RHOASIGNOR-271700
SRCphosphorylation
→
down-regulates activity 		RHOASIGNOR-271702