Entity Details

Name BCR-ABL_Tyr66
ID P61586
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCRHOATyr66DTAGQEDyDRLRPLSphosphorylation
down-regulates activity		23027962SIGNOR-271701
BCR-ABLRHOATyr66DTAGQEDyDRLRPLSphosphorylation
down-regulates activity		23027962SIGNOR-271699
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
RHOA
PTyr66		phosphorylation
down-regulates
⊣		RHOA23027962SIGNOR-271701
BCR-ABLphosphorylation
up-regulates
→
RHOA
PTyr66		phosphorylation
down-regulates
⊣		RHOA23027962SIGNOR-271699
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
down-regulates activity 		RHOASIGNOR-271701
BCR-ABLphosphorylation
→
down-regulates activity 		RHOASIGNOR-271699