Entity Details

Name PRKACA_Ser188
ID P61586
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKACARHOASer188ARRGKKKsGCLVLphosphorylation
down-regulates activity		12654918SIGNOR-250047
PRKCERHOASer188ARRGKKKsGCLVLphosphorylation
up-regulates activity		24191200SIGNOR-279477
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKACAphosphorylation
up-regulates
→
RHOA
PSer188		phosphorylation
down-regulates
⊣		RHOA12654918SIGNOR-250047
PRKCEphosphorylation
up-regulates
→
RHOA
PSer188		phosphorylation
up-regulates
→		RHOA24191200SIGNOR-279477
Regulator Mechanism/Effect Target SIGNOR-ID
PRKACAphosphorylation
→
down-regulates activity 		RHOASIGNOR-250047
PRKCEphosphorylation
→
up-regulates activity 		RHOASIGNOR-279477