Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
RPS6KA1	RPS6	Ser240 View in OncoXplorer	RLSSLRAsTSKSESS	phosphorylation up-regulates	21233202	SIGNOR-171243
RPS6K	RPS6	Ser240 View in OncoXplorer	RLSSLRAsTSKSESS	phosphorylation up-regulates	21233202	SIGNOR-252765
PAK2	RPS6	Ser240 View in OncoXplorer	RLSSLRAsTSKSESS	phosphorylation unknown	1985906	SIGNOR-250233

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
RPS6KA1	phosphorylation up-regulates →	RPS6 PSer240	phosphorylation up-regulates →	RPS6	21233202	SIGNOR-171243
RPS6K	phosphorylation up-regulates →	RPS6 PSer240	phosphorylation up-regulates →	RPS6	21233202	SIGNOR-252765
PAK2	phosphorylation up-regulates →	RPS6 PSer240	phosphorylation down-regulates ⊣	RPS6	1985906	SIGNOR-250233

Regulator	Mechanism/Effect	Target	SIGNOR-ID
RPS6KA1	phosphorylation → up-regulates	RPS6	SIGNOR-171243
RPS6K	phosphorylation → up-regulates	RPS6	SIGNOR-252765
PAK2	phosphorylation → unknown	RPS6	SIGNOR-250233