| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BCR-ABL | GRB2 | Tyr52 | DGFIPKNyIEMKPHP | phosphorylation down-regulates activity | 20554525 | SIGNOR-246293 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BCR-ABL | phosphorylation up-regulates → | GRB2 PTyr52 | phosphorylation down-regulates ⊣ | GRB2 | 20554525 | SIGNOR-246293 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| BCR-ABL | phosphorylation → down-regulates activity | GRB2 | SIGNOR-246293 |
