Entity Details

Name RAC1
ID P63000
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCRAC1–phosphorylation
up-regulates		17991704SIGNOR-158954
PTK2RAC1–phosphorylation
up-regulates activity		22163037SIGNOR-279652
SRCRAC1Tyr64DTAGQEDyDRLRPLSphosphorylation
up-regulates activity		30544910SIGNOR-280132
AKT1RAC1Ser71
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YDRLRPLsYPQTDVFphosphorylation
down-regulates activity		10617634SIGNOR-252576
LRRK1RAC1–phosphorylation
up-regulates activity		27600824SIGNOR-279626
AKTRAC1Ser71
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YDRLRPLsYPQTDVFphosphorylation
down-regulates activity		10617634SIGNOR-248036
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
RAC1
PTyr64		phosphorylation
up-regulates
→		RAC130544910SIGNOR-280132
AKT1phosphorylation
up-regulates
→
RAC1
PSer71		phosphorylation
down-regulates
⊣		RAC110617634SIGNOR-252576
AKTphosphorylation
up-regulates
→
RAC1
PSer71		phosphorylation
down-regulates
⊣		RAC110617634SIGNOR-248036
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates 		RAC1SIGNOR-158954
PTK2phosphorylation
→
up-regulates activity 		RAC1SIGNOR-279652
SRCphosphorylation
→
up-regulates activity 		RAC1SIGNOR-280132
AKT1phosphorylation
→
down-regulates activity 		RAC1SIGNOR-252576
LRRK1phosphorylation
→
up-regulates activity 		RAC1SIGNOR-279626
AKTphosphorylation
→
down-regulates activity 		RAC1SIGNOR-248036