Entity Details

Name EGFR_Tyr154
ID P63096
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
EGFRGNAI1Tyr154QLNDSAAyYLNDLDRphosphorylation
up-regulates activity		33139573SIGNOR-277227
FLT1GNAI1Tyr154QLNDSAAyYLNDLDRphosphorylation
up-regulates activity		33139573SIGNOR-277230
PDGFRBGNAI1Tyr154QLNDSAAyYLNDLDRphosphorylation
up-regulates activity		33139573SIGNOR-277233
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
EGFRphosphorylation
up-regulates
→
GNAI1
PTyr154		phosphorylation
up-regulates
→		GNAI133139573SIGNOR-277227
FLT1phosphorylation
up-regulates
→
GNAI1
PTyr154		phosphorylation
up-regulates
→		GNAI133139573SIGNOR-277230
PDGFRBphosphorylation
up-regulates
→
GNAI1
PTyr154		phosphorylation
up-regulates
→		GNAI133139573SIGNOR-277233
Regulator Mechanism/Effect Target SIGNOR-ID
EGFRphosphorylation
→
up-regulates activity 		GNAI1SIGNOR-277227
FLT1phosphorylation
→
up-regulates activity 		GNAI1SIGNOR-277230
PDGFRBphosphorylation
→
up-regulates activity 		GNAI1SIGNOR-277233