Entity Details

Name PITX1
ID P78337
Role substrate
Enzymatic Domains
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPN1PITX1Tyr179EDVYAAGySYNNWAAdephosphorylation
down-regulates quantity by destabilization		27752061SIGNOR-276973
PTPN1PITX1Tyr160LDLCKGGyVPQFSGLdephosphorylation
down-regulates quantity by destabilization		27752061SIGNOR-276974
ABL1PITX1–phosphorylation
up-regulates activity		20563669SIGNOR-280171
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTPN1dephosphorylation
down-regulates
⊣
PITX1
PTyr179		dephosphorylation
up-regulates
→		PITX127752061SIGNOR-276973
PTPN1dephosphorylation
down-regulates
⊣
PITX1
PTyr160		dephosphorylation
up-regulates
→		PITX127752061SIGNOR-276974
Regulator Mechanism/Effect Target SIGNOR-ID
PTPN1dephosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		PITX1SIGNOR-276973
PTPN1dephosphorylation
img/direct_inhibition.png
down-regulates quantity by destabilization 		PITX1SIGNOR-276974
ABL1phosphorylation
→
up-regulates activity 		PITX1SIGNOR-280171