Name PITX1
Full Name Pituitary homeobox 1
Synonyms Hindlimb-expressed homeobox protein backfoot, Homeobox protein PITX1, Paired-like homeodomain transcription factor 1 | BFT, PTX1
Primary ID P78337
Links - -
Type protein
Relations 4
Function Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.



Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding PITX1 0.17
Publications: 1 Organism: Mus Musculus
+ up-regulates quantity by expression img/indirect-activation.png transcriptional regulation LHB 0.18
Publications: 1 Organism: Mus Musculus
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation GNRH1 0.06
Publications: 1 Organism: Mus Musculus
+ up-regulates activity img/direct-activation.png binding POU1F1 0.38
Publications: 1 Organism: In Vitro