| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RET | PRKDC | Ser2056 | VQSYSYSsQDPRPAT | phosphorylation up-regulates activity | 26065416 | SIGNOR-279275 |
| PRKDC | PRKDC | Ser2056 | VQSYSYSsQDPRPAT | phosphorylation up-regulates | 17189255 | SIGNOR-151445 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RET | phosphorylation up-regulates → | PRKDC PSer2056 | phosphorylation up-regulates → | PRKDC | 26065416 | SIGNOR-279275 |
| PRKDC | phosphorylation up-regulates → | PRKDC PSer2056 | phosphorylation up-regulates → | PRKDC | 17189255 | SIGNOR-151445 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RET | phosphorylation → up-regulates activity | PRKDC | SIGNOR-279275 |
| PRKDC | phosphorylation → up-regulates | PRKDC | SIGNOR-151445 |
